Key result
Increasing HbA1c was positively associated with increased brachial-ankle pulse wave velocity in subjects with normoglycaemia and impaired glucose metabolism (P from 0.04 to <0.001).
Population
1249 subjects from the Guangzhou Biobank Cohort Study-CVD, including normoglycemia, impaired glucose…
Design
Cohort
Authors
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May signal early vascular risk from glycemia without diabetes; leaves open whether HbA1c reduction slows stiffness progression.
Cohort (n=1,249)
p-value: p=0.04 to <0.001
Chronic glycemia, even in the absence of overt diabetes, is associated with increased arterial stiffness, highlighting its role in early vascular disease risk.
Xu et al. (2010) conducted a cohort in Arterial stiffness (n=1,249). Glycaemic status and HbA1c was evaluated on Brachial-ankle pulse wave velocity (baPWV) (p=0.04 to <0.001). Increasing HbA1c was positively associated with increased brachial-ankle pulse wave velocity in subjects with normoglycaemia and impaired glucose metabolism (P from 0.04 to <0.001).
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