Key result
In rat arteries in vitro, dynamic elastic modulus and wall viscosity increased with circumferential wall stress, with values virtually identical under norepinephrine and papaverine for a given stress.
Population
Segments of the abdominal aorta, carotid artery, and tail artery of normotensive rats in vitro
Design
Preclinical
Authors
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Arterial viscoelasticity depends on wall stress independent of tone in this rat model; leaves open relevance to human vascular disease.
In normotensive rat arteries in vitro, dynamic elastic modulus and arterial wall viscosity increase with circumferential wall stress but are independent of smooth muscle tone for a given stress range.
Bauer et al. (1982) studied this question. Norepinephrine (NE) vs. Papaverine (PAP) was evaluated on Quotient of dynamic (Ed) and quasistatic elastic modulus (ESt) and arterial wall viscosity (eta w). In rat arteries in vitro, dynamic elastic modulus and wall viscosity increased with circumferential wall stress, with values virtually identical under norepinephrine and papaverine for a given stress.
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