Key result
Treatment of type B aortic dissection with a novel single-branched aortic stent graft demonstrated acceptable safety, with 4.5% 30-day mortality and 97.7% device technical success.
Why the study?
Intervention on type B dissection often requires proximal stent graft landing between the left common carotid artery and LSA, which may be addressed by the GORE TAG thoracic branch endoprosthesis to preserve the LSA.
Does a single-branched aortic stent graft provide safe and effective outcomes in patients with type B aortic dissection?
Does a single-branched aortic stent graft provide safe and effective outcomes in patients with type B aortic dissection?
A novel single-branched aortic stent graft demonstrates high technical success and acceptable safety at 1 year for patients with type B aortic dissection requiring left subclavian artery preservation.
May enable LSA preservation during type B dissection repair; leaves open need for randomized comparisons.
BACKGROUND: Intervention on type B dissection frequently requires landing the proximal edge of the stent graft between the left common carotid artery and left subclavian artery (LSA). The GORE TAG thoracic branch endoprosthesis is a technology that allows LSA preservation with a single internal branch. METHODS: This study was a prospective nonrandomized single-arm clinical trial of patients with type B aortic dissection who were treated with the single-branched device. Patients with operative indications for acute, chronic, or residual type B dissections that originated distal to the origin of an LSA suitable for branch graft placement were eligible for the study. Native aortic and surgical graft proximal landing zones were eligible. RESULTS: Of the 132 patients, there were 25 (18.9%) acute type B dissections, 79 (59.8%) chronic type B dissections, and 28 (21.1%) residual dissections after previous open type A repair. Percutaneous access was used in 105 (79.5%) patients. Overall, 30-day mortality occurred in 6 patients (4.5%). The overall 30-day stroke rate was 2 of 132 (1.5%), and the 1-year freedom from stroke was 96.8%. Device technical success and procedural success were achieved in 129 of 132 (97.7%) and 110 of 132 (83.3%) patients, respectively, and there was 1 instance of loss of side branch patency. No persistent antegrade false lumen flow was observed. CONCLUSIONS: In this study of a novel branched endograft device to preserve the LSA in patients with type B dissection undergoing thoracic endovascular aortic repair, we demonstrate acceptable safety and efficacy outcomes at 1 year.
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Desai et al. (2024) studied Type B aortic dissection (n=132). GORE TAG thoracic branch endoprosthesis was evaluated on 30-day mortality. Treatment of type B aortic dissection with a novel single-branched aortic stent graft demonstrated acceptable safety, with 4.5% 30-day mortality and 97.7% device technical success.
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