Key result
The understanding of hypertension evolved from a compensatory mechanism to a clinical entity, aided by the establishment of experimental animal models for neurogenic and renal hypertension.
Design
Review
Authors
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Historical framing offers no immediate clinical changes; leaves open integration of early animal models into modern hypertension research.
Provides a historical perspective on the recognition of hypertension as a clinical entity and the development of experimental animal models.
Page et al. (1952) conducted a review in Hypertension. The understanding of hypertension evolved from a compensatory mechanism to a clinical entity, aided by the establishment of experimental animal models for neurogenic and renal hypertension.
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