Key result
Lumbar epidural anesthesia to T4 prevented significant increases in norepinephrine and epinephrine in response to abdominal surgery compared to general anesthesia.
Why the study?
Does lumbar epidural anesthesia prevent plasma catecholamine increases compared to general anesthesia in patients undergoing abdominal aortic aneurysm repair?
Population
24 patients undergoing abdominal aortic aneurysm (AAA) repair
Comparison
Lumbar epidural anesthesia to T4 sensory level… vs High dose of opioid anesthetic
Design
Cohort
Follow-up
10 min after cross-clamping
Authors
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Epidural to T4 may blunt catecholamine response in abdominal aortic repair; leaves open outcome benefits pending randomized confirmation.
Does lumbar epidural anesthesia prevent plasma catecholamine increases compared to general anesthesia in patients undergoing abdominal aortic aneurysm repair?
p-value: p=<0.05
Lumbar epidural anesthesia to T4 prevents the increase in norepinephrine and epinephrine in response to abdominal surgery compared to general anesthesia.
Gold et al. (1994) studied Abdominal aortic aneurysm (AAA) (n=24). Lumbar epidural anesthesia (LEA) with light general anesthetic vs. General anesthesia (GA) with high dose of opioid anesthetic was evaluated on Plasma catecholamine levels (norepinephrine and epinephrine) and systemic vascular resistance (p=<0.05). Lumbar epidural anesthesia to T4 prevented significant increases in norepinephrine and epinephrine in response to abdominal surgery compared to general anesthesia.
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