Key result
Estimated pulse wave velocity using a single-cuff method mainly reflects the entered chronological age (R²=0.90) rather than true vascular properties, showing only a modest correlation with measured PWV (R²=0.40) that disappears after age adjustment.
Why the study?
Pulse wave velocity predicts cardiovascular risk, and single-cuff oscillometric methods are used clinically to estimate it, but their utility for assessing vascular health in master athletes and accuracy versus two-cuff measurements required evaluation.
Does single-cuff oscillometric estimation of pulse wave velocity accurately reflect true vascular properties compared to direct two-cuff measurement?
Population
129 master athletes aged 35-86 years and 24 healthy persons aged 24-55 years
Comparison
Single-cuff oscillometric estimated PWV vs direct two-cuff PWV measurement
Design
Observational comparison study
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Single-cuff PWV estimates mainly reflect age, not vascular properties; leaves open true effects of lifelong exercise pending validated measures.
Cross-Sectional (n=153)
Yes
Does single-cuff oscillometric estimation of pulse wave velocity accurately reflect true vascular properties compared to direct two-cuff measurement?
Effect estimate: R² 0.40
p-value: p=<0.05
Single-cuff estimated pulse wave velocity mainly reflects the patient's entered age rather than true vascular stiffness, limiting its utility for detecting exercise-induced vascular benefits.
A 2022 study conducted a cross-sectional in Vascular stiffness (n=153). Single-cuff oscillometric estimated pulse wave velocity vs. Two-cuff measured pulse wave velocity was evaluated on Correlation between estimated and measured pulse wave velocity (R² 0.40, p=<0.05). Estimated pulse wave velocity using a single-cuff method mainly reflects the entered chronological age (R²=0.90) rather than true vascular properties, showing only a modest correlation with measured PWV (R²=0.40) that disappears after age adjustment.
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