Key result
A CD4 count lower than 250 cells/mm3 in HIV-infected patients was significantly associated with an increased risk of developing atrial fibrillation (OR 3.62).
Why the study?
Are lower CD4 counts associated with an increased risk of developing atrial fibrillation in HIV infected patients?
Case-Control (n=80)
Yes
Are lower CD4 counts associated with an increased risk of developing atrial fibrillation in HIV infected patients?
Odds Ratio: 3.62 (95% CI 1.34–9.77)
Absolute Event Rate: 47.5% vs 20%
p-value: p=0.017
HIV infection, particularly with lower CD4 counts, is associated with an increased susceptibility to developing atrial fibrillation.
Low CD4 counts may warrant closer AF monitoring in HIV; leaves open whether immune recovery reduces incidence.
The data supports the presence of a relationship between HIV and AF. Patients with lower CD4 counts are more susceptible to develop AF.
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Elnahar et al. (2012) conducted a case-control in HIV infection and Atrial Fibrillation (n=80). CD4 count < 250 cells/mm3 vs. CD4 count ≥ 250 cells/mm3 was evaluated on Development of atrial fibrillation (OR 3.62, 95% CI 1.34 to 9.77, p=0.017). A CD4 count lower than 250 cells/mm3 in HIV-infected patients was significantly associated with an increased risk of developing atrial fibrillation (OR 3.62).
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