Why the study?
Arterial hypertension remains poorly controlled in clinical practice, prompting this focus issue dedicated to topics ranging from hypertension epidemiology and risk stratification to control strategies.
Population
Patients with or at risk for arterial hypertension across various cohorts discussed in the issue.
Comparison
Various hypertension management and risk… vs Standard care, standard blood pressure targets…
Design
Editorial
Key result
Intensive blood pressure treatment lowered total mortality (OR 0.75; 95% CI 0.60-0.94), but severe adverse events mediated an increase in mortality (OR 1.03; 95% CI 1.01-1.05) in older adults.
Authors
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HSBP may drive CV risk in elderly hypertension; leaves open whether targeting it improves outcomes in trials.
Odds Ratio: 0.75 (95% CI 0.6–0.94)
This issue focus summarizes recent advances in hypertension, emphasizing the benefits and risks of intensive blood pressure control and the value of enhanced risk stratification tools.
Parati et al. (2023) conducted an editorial in Arterial hypertension. Intensive blood pressure treatment vs. Standard treatment was evaluated on Total mortality (OR 0.75, 95% CI 0.60-0.94). Intensive blood pressure treatment lowered total mortality (OR 0.75; 95% CI 0.60-0.94), but severe adverse events mediated an increase in mortality (OR 1.03; 95% CI 1.01-1.05) in older adults.
Synapse has enriched 5 closely related papers on similar clinical questions. Consider them for comparative context: