Key result
A hemoglobin concentration increase of >3 g/dl on postoperative day 1 was independently associated with a significantly higher risk of acute kidney injury (adjusted OR 6.94) compared to no increase.
Population
220 patients who underwent congenital cardiac surgery between January and December 2012 at a single center.
Design
Cohort
Follow-up
7 days postoperatively
Authors
Loading...
May support targeting anesthesia parameters to reduce pediatric postoperative AKI; hypothesis-generating pending prospective validation.
Cohort (n=220)
No
Odds Ratio: 6.94 (95% CI 2.33–20.69)
Absolute Event Rate: 78.6% vs 26.4%
p-value: p=0.001
Younger age, longer cardiopulmonary bypass time, low preoperative hemoglobin, and significant postoperative hemoconcentration are independent risk factors for acute kidney injury following congenital cardiac surgery.
Park et al. (2016) conducted a cohort in Congenital heart disease requiring cardiac surgery (n=220). Hemoglobin concentration increase (>3 g/dl) on postoperative day 1 vs. No increase or decrease in hemoglobin concentration was evaluated on Incidence of acute kidney injury (AKI) within 7 days postoperatively according to KDIGO criteria (adjusted OR 6.94, 95% CI 2.33-20.69, p=0.001). A hemoglobin concentration increase of >3 g/dl on postoperative day 1 was independently associated with a significantly higher risk of acute kidney injury (adjusted OR 6.94) compared to no increase.
Synapse has enriched 5 closely related papers on similar clinical questions. Consider them for comparative context: