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November 30, 2023The Professional Medical JournalOpen Access

Incidence and risk factors for acute kidney injury in children with congenital heart disease undergoing cardiac surgery in a tertiary care center.

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Key result

Congenital heart surgery carries a 6.5% AKI incidence, associated with prolonged CPB and hypotension.

  • n=93

Why the study?

The incidence and risk factors for acute kidney injury in children with congenital heart disease undergoing cardiac surgery were not well defined in this setting.

What is the incidence and what are the risk factors for acute kidney injury in patients with congenital heart disease undergoing cardiac surgery?

Population

93 patients with congenital heart disease undergoing cardiac surgery in a tertiary care center in Pakistan

Comparison

Patients who developed AKI vs those who did not develop AKI post-surgery

Design

Cross-sectional study

Follow-up

Total duration of PCICU stay

Authors

RKRajab Ali KhokharMRMujeeb Ur RehmanSZSaad Bader Zakai

Discussion

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Member takes

Overview

AKI incidence and risk factors after pediatric CHD surgery quantified; leaves open whether findings warrant targeted prevention trials.

Study Design

Type

Cross-Sectional (n=93)

Multicenter

No

Structured PICO

What is the incidence and what are the risk factors for acute kidney injury in patients with congenital heart disease undergoing cardiac surgery?

P
Population
93 patients (mean age 9.71 years, 46.2% female) with congenital heart disease undergoing cardiac surgery, monitored during their pediatric cardiac intensive care unit stay.
E
Exposure
Open or closed heart surgery for congenital heart defects
O
Outcome
Development of acute kidney injury (AKI) labeled as per RIFLE criteria during PCICU stayhard clinical

Post-operative acute kidney injury occurred in 6.5% of patients undergoing congenital heart disease surgery and was strongly associated with prolonged cardiopulmonary bypass time, hypotension, and increased mortality.

Limitations

  • Observational study design makes it difficult to establish causality
  • Only in-hospital outcomes were noted
  • Observational study design making it difficult to establish causality
  • Only noted in-hospital outcomes

Cite This Study

Khokhar et al. (2023) conducted a cross-sectional in Congenital heart disease (n=93). Cardiac surgery for congenital heart disease was evaluated on Incidence of acute kidney injury (AKI). The incidence of acute kidney injury following cardiac surgery for congenital heart disease was 6.5%, with significant risk factors including prolonged cardiopulmonary bypass time and hypotension.

synapsesocial.com/papers/6aaf2e9974b24cee3ca5efbchttps://doi.org/10.29309/tpmj/2023.30.12.7766
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