Key result
Prolonged aortic clamping is linked to ~152% higher AKI risk in pediatric cardiac surgery.
Why the study?
The study was conducted to analyze the risk factors and outcomes of acute kidney injury in young children with congenital heart disease after cardiac surgery.
What are the risk factors for and clinical outcomes of acute kidney injury in young children undergoing cardiac surgery for congenital heart disease?
Population
137 young children with CHD after cardiac surgery
Comparison
Patients developing AKI vs those without AKI
Design
Observational study
Authors
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Supports vigilant AKI monitoring after pediatric cardiac surgery; leaves open whether shortening aortic clamp time reduces incidence.
Cohort (n=137)
No
What are the risk factors for and clinical outcomes of acute kidney injury in young children undergoing cardiac surgery for congenital heart disease?
Effect estimate: OR 2.52 (95% CI 1.81-3.05)
p-value: p=<0.01
Acute kidney injury is a frequent complication (40.9%) after pediatric cardiac surgery for congenital heart disease, driven by factors like prolonged bypass and younger age, and is associated with significantly increased hospital mortality.
Исмаилов et al. (2023) conducted a cohort in Congenital heart disease (n=137). Prolonged aortic clamping vs. Shorter aortic clamping was evaluated on Acute kidney injury (AKI) (OR 2.52, 95% CI 1.81-3.05, p=<0.01). In young children undergoing cardiac surgery, the incidence of acute kidney injury was 40.9%, with prolonged aortic clamping significantly increasing the risk (OR 2.52).
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