Key result
Stentless thoracic endovascular aortic repair can result in postimplantation syndrome, demonstrating that this inflammatory response can occur even in the absence of a stent graft.
Why the study?
Postimplantation syndrome is well-documented with stent graft use, but its occurrence in the absence of stent grafts remains poorly understood.
Case Report (n=1)
This case demonstrates that postimplantation syndrome can occur after stentless endovascular aortic repair, suggesting prophylactic anti-inflammatory therapy may be warranted for large-volume aneurysms or false lumen thrombosis.
PIS may occur after stentless TEVAR; leaves open graft-independent mechanisms and requires confirmation in larger studies.
Postimplantation syndrome (PIS) is a noninfectious systemic inflammatory response that often follows endovascular aneurysm repair, historically presumed to be a reaction to implanted graft materials. Although well-documented with stent graft use, PIS in the absence of stent grafts remains poorly understood. We present an instance of PIS after stentless thoracic endovascular aortic repair, which involves embolizing intimal tears with plugs and/or coils. This case highlights the need for further investigation into the pathophysiology of PIS. PIS can occur in the absence of a stent graft; prophylactic anti-inflammatory therapy may be warranted during endovascular interventions with large-volume aneurysms or false lumen thrombosis.
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Blackman et al. (2025) conducted a case report in Chronic aortic dissection (n=1). Stentless thoracic endovascular aortic repair was evaluated on Postimplantation syndrome. Stentless thoracic endovascular aortic repair can result in postimplantation syndrome, demonstrating that this inflammatory response can occur even in the absence of a stent graft.
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