Key result
The immediate upstream promoter of the human MAFbx gene mediates its developmental expression and tissue specificity in muscle lineage cells.
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Does not yet inform clinical decisions on muscle wasting; leaves open the MAFbx promoter as a regulatory target for further research.
Zhao et al. (2005) studied Muscle loss. Human MAFbx gene upstream promoter analysis was evaluated on MAFbx expression and promoter activity. The immediate upstream promoter of the human MAFbx gene mediates its developmental expression and tissue specificity in muscle lineage cells.
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