Key result
One-anastomosis gastric bypass and Roux-en-Y gastric bypass resulted in similar body mass index at 6 months postoperative (32.1 vs 31.8 kg/m2, P=0.91).
Why the study?
One-anastomosis gastric bypass is simpler than Roux-en-Y gastric bypass, but biliary reflux can occur and impair outcomes.
Does one-anastomosis gastric bypass improve weight loss, patient satisfaction, and quality of life compared to Roux-en-Y gastric bypass in patients with morbid obesity?
RCT (n=20)
Single-blind
Prospective randomization
No
Does one-anastomosis gastric bypass improve weight loss, patient satisfaction, and quality of life compared to Roux-en-Y gastric bypass in patients with morbid obesity?
Absolute Event Rate: 32.1% vs 31.8%
p-value: p=0.91
One-anastomosis gastric bypass and Roux-en-Y gastric bypass provide similar short-term weight loss, patient satisfaction, and quality of life without significant differences in mucosal inflammation.
Short-term equivalence in weight loss, QoL, and mucosal findings between OAGB and RYGB in this small RCT; leaves open long-term safety and durability.
Background: One-anastomosis gastric bypass (OAGB) is a simpler procedure than Roux-en-Y gastric bypass (RYGB); however, biliary reflux can occur and impair outcomes. This study aimed to compare outcomes of OAGB and RYGB. Methods: Twenty patients with morbid obesity were randomized prospectively into two groups: OAGB (n=10) or RYGB (n=10). Quality of life (36-item short-form health survey [SF-36]), satisfaction (Visick scale), and body mass index (BMI) were evaluated before and 6 months after the operation. All patients underwent esophagogastroduodenoscopy with gastric and esophageal mucosal biopsies at 3 and 6 months after their operation. Results: =0.76) inflammation grade at three or 6 months between the two groups. Conclusion: OAGB and RYGB are equally effective in terms of weight loss, patient satisfaction, and quality of life improvement at 6 months after the procedures. Inflammation grade and cellular damage in the gastric pouch and in the esophagus were similar.
No takes yet. Share an insight, caveat, or question.
Katayama et al. (2021) conducted an RCT in Morbid obesity (n=20). One-anastomosis gastric bypass (OAGB) vs. Roux-en-Y gastric bypass (RYGB) was evaluated on Body mass index (BMI) at 6 months postoperative (p=0.91). One-anastomosis gastric bypass and Roux-en-Y gastric bypass resulted in similar body mass index at 6 months postoperative (32.1 vs 31.8 kg/m2, P=0.91).
Synapse has enriched 5 closely related papers on similar clinical questions. Consider them for comparative context: