Key result
One-anastomosis gastric bypass resulted in similar total weight loss compared to Roux-en-Y gastric bypass at 12 months (26.1% vs 25.4%; p=0.635).
Why the study?
Little robust evidence exists to prove whether one-anastomosis gastric bypass is metabolically superior to Roux-en-Y gastric bypass when bypass lengths are standardized.
Does one-anastomosis gastric bypass improve weight loss and metabolic outcomes compared to Roux-en-Y gastric bypass in bariatric patients?
Population
121 bariatric patients in two Finnish University Hospitals
Comparison
RYGB (n = 61) vs OAGB (n = 60) with standardized bypass length
Design
Multicenter randomized controlled trial
Follow-up
12 months
Authors
Loading...
Standardized bypass lengths yield similar outcomes in retrospective OAGB vs RYGB data; leaves open metabolic superiority and requires prospective confirmation.
RCT (n=121)
randomized
Yes
Does one-anastomosis gastric bypass improve weight loss and metabolic outcomes compared to Roux-en-Y gastric bypass in bariatric patients?
Absolute Event Rate: 26.1% vs 25.4%
p-value: p=0.635
RYGB and OAGB provide comparable weight loss and metabolic improvements at 1 year, but RYGB is associated with greater reductions in antihypertensive medications and less vitamin D deficiency.
Heinonen et al. (2023) conducted an RCT in Obesity (n=121). One-anastomosis gastric bypass (OAGB) vs. Roux-en-Y gastric bypass (RYGB) was evaluated on Total weight loss at 12 months (p=0.635). One-anastomosis gastric bypass resulted in similar total weight loss compared to Roux-en-Y gastric bypass at 12 months (26.1% vs 25.4%; p=0.635).
Synapse has enriched 5 closely related papers on similar clinical questions. Consider them for comparative context: