What question did this study set out to answer?

To identify and characterize clinical features and biomarkers associated with blood eosinophilia in adult asthma patients.

The characterization of asthma with blood eosinophilia in adults in Latin America

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Cross-sectional study finds blood eosinophilia in over a third of asthmatic adults, indicating heightened disease severity and poorer control.

To identify and characterize clinical features and biomarkers associated with blood eosinophilia in adult asthma patients.
Conducted a cross-sectional study involving 164 adult asthma patients aged 18 years or older.
Defined blood eosinophilia as a peripheral blood eosinophil count ≥400 cells/mm³.
Identified associated factors using multivariate logistic regression and evaluated diagnostic accuracy using receiver operating characteristic (ROC) curves.
Blood eosinophilia was present in 37.8% (95% CI: 30.7–45.4%) of adult asthma patients.
Blood eosinophilia was significantly associated with age <50 years (OR 3.25; 95% CI: 1.33–7.94), serum IgE ≥300 UI/mL (OR 2.32; 95% CI: 1.14–4.75), an Asthma Control Test score <20 (OR 3.10; 95% CI: 1.35–4.75), and baseline FEV1/FVC <70% (OR 2.68; 95% CI: 1.28–5.59).
An Asthma Control Test score <20 and age <50 years demonstrated the highest sensitivity (>80% each), while serum IgE ≥300 UI/mL showed the highest specificity (~68%), and an ACT score <20 yielded the highest AUC (68%).

Bedolla‐Barajas et al. (2018) studied this question.

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Cross-sectional study finds blood eosinophilia in over a third of asthmatic adults, indicating heightened disease severity and poorer control.