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November 1, 1960HeartOpen Access

Electrocardiographic Changes in Hypothermia

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Key result

Experimental hypothermia in animals induces characteristic electrocardiographic changes including progressive bradycardia, prolongation of the P-R, QRS, and Q-T intervals, and J deflections.

Why the study?

What are the electrocardiographic changes observed in experimental animals at various stages of cooling?

Population

Experimental animals

Design

Preclinical

Authors

NWN. A. WynneNorth Tyneside General HospitalJFJ. FullerUniversity of GothenburgPSP. SzékelyUniversitatea de Medicină, Farmacie, Științe și Tehnologie „George Emil Palade” din Târgu Mureș

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Implication

Characterizes ECG changes in hypothermic animal models; leaves open translation to human therapeutic hypothermia.

Structured PICO

What are the electrocardiographic changes observed in experimental animals at various stages of cooling?

P
Population
Experimental animals
E
Exposure
Hypothermia (various stages of cooling)
O
Outcome
Electrocardiographic changessurrogate

Hypothermia induces characteristic electrocardiographic changes including progressive bradycardia, interval prolongations, and a pathognomonic J deflection.

Cite This Study

Wynne et al. (1960) studied Hypothermia. Hypothermia was evaluated on Electrocardiographic changes. Experimental hypothermia in animals induces characteristic electrocardiographic changes including progressive bradycardia, prolongation of the P-R, QRS, and Q-T intervals, and J deflections.

synapsesocial.com/papers/6a97e17190d51c6c12fae4efhttps://doi.org/10.1136/hrt.22.5.642
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Also Consider

Synapse has enriched 4 closely related papers on similar clinical questions. Consider them for comparative context:

  1. 1Sensitivity of the Hypothermic Myocardium to Calcium1957 · 18 citations
  2. 2ELECTROCARDIOGRAPHIC CHANGES IN INDUCED HYPOTHERMIA IN MAN1957 · 46 citations
  3. 3ITS POSSIBLE ROLE IN CARDIAC SURGERY1950 · 716 citations
  4. 4THE SIGNIFICANCE OF CHANGES IN THE ELECTROCARDIOGRAM IN HYPOTHERMIA1959 · 104 citations