Key result
Prolonging atrioventricular delay in patients with DDD pacemakers revealed a significant negative correlation between critical PQ intervals inducing diastolic MR and PCWP (r = -0.85, P<0.001).
Why the study?
Does prolonging AV delay induce diastolic mitral regurgitation and how does it relate to cardiac function in patients with DDD pacemakers?
Population
50 patients (mean age 71.3 +/- 11.3 years) implanted with DDD pacemakers.
Design
Cross-sectional
Authors
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Diastolic MR with AV delay prolongation may signal higher PCWP in DDD pacemaker patients; leaves open whether this marker guides optimization.
Observational (n=50)
Does prolonging AV delay induce diastolic mitral regurgitation and how does it relate to cardiac function in patients with DDD pacemakers?
Effect estimate: r = -0.85
p-value: p=<0.001
The appearance of diastolic mitral regurgitation during AV delay prolongation in DDD pacemaker patients is strongly correlated with baseline cardiac function as measured by PCWP.
Ishikawa et al. (1991) conducted an observational in Patients implanted with DDD pacemakers (n=50). Prolonging atrioventricular (AV) delay was evaluated on Correlation between critical PQ intervals for the appearance of diastolic MR and PCWP (r = -0.85, p=<0.001). Prolonging atrioventricular delay in patients with DDD pacemakers revealed a significant negative correlation between critical PQ intervals inducing diastolic MR and PCWP (r = -0.85, P<0.001).
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