Synapse
⌘+K
Synapse
PulseExploreClubsResearchersJournals
Instagram
HomeClubsExplore
September 2, 2026BMC GeriatricsOpen Access

Implementing an exercise intervention for sarcopenia in oldest-old nursing home residents: protocol for a pragmatic cluster-randomized controlled trial (SCOPE Study)

View Full Paper
Ask AI
Bookmark
Share

Authors

CXCheng XiangLLLu LiJZJianzhi Zhao

Discussion

Loading...

Member takes

Overview

Cluster-randomized trial reports exercise intervention protocols for sarcopenia in oldest-old residents, highlighting scalable management frameworks for long-term care.

Key Points

  • Evaluate the feasibility and effectiveness of caregiver-led modified Baduanjin, resistance training, and combined exercise programs for managing sarcopenia in oldest-old nursing home residents.
  • Pragmatic, cluster-randomized controlled trial (ChiCTR2500107315) recruiting 104 residents aged ≥75 years with sarcopenia across residential buildings in a nursing home in Hangzhou, China.
  • Participants are randomized into four groups: Modified Baduanjin, Resistance Training, Combined Exercise, and Control for a 48-week caregiver-delivered, video-guided intervention.
  • Primary endpoint is a composite sarcopenia Z-score combining handgrip strength, Short Physical Performance Battery, and appendicular skeletal muscle mass index assessed up to 2 years post-intervention.
  • Trial protocol: participant enrollment and long-term intervention delivery are underway.
  • Primary outcome analysis will evaluate composite sarcopenia Z-score trajectories across all three active exercise groups versus standard care at weeks 12, 24, 48, and years 1 and 2.

Cite This Study

Xiang et al. (2026) studied this question.

synapsesocial.com/papers/6a97e249c562ede874ec6584https://doi.org/10.1186/s12877-026-08002-8
View Full Paper
Ask AI
Bookmark
Share

Also Consider

Synapse has enriched 5 closely related papers on similar clinical questions. Consider them for comparative context:

  1. 1Effect of a combined exercise and nutrition program on sarcopenia in older adults: a randomised controlled trial in primary care2025
  2. 2Feasibility and efficacy of square dancing and elastic band training for sarcopenia in nursing home residents2025
  3. 3Effectiveness of home-based exercise interventions in the management of Sarcopenia in older adults: a systematic review of randomized controlled trials2026
  4. 4Approach to sarcopenia in older adults: a systematic review of dietary and exercise interventions in the primary care setting2026
  5. 5Efficacy of Baduanjin Exercise for Sarcopenia in Older Adults: A 24‐Week Randomized Controlled Trial2025