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September 2, 2026International Journal of Women s HealthOpen Access

Clinical and Metabolic Factors Associated with Comorbidities of Thyroid and Breast Diseases in Women Aged 25–55 Years

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Authors

JHJiuying HuBengbu Medical CollegeYDYu DingAnhui Medical UniversityJWJuan WuNanjing University of Chinese Medicine

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Overview

Observational study reveals metabolic and clinical factors linked to combined thyroid and breast conditions in young to middle-aged women, highlighting key targets for integrated screening.

Key Points

  • Identify clinical and metabolic factors associated with the co-occurrence of thyroid and breast diseases in adult women.
  • Conducted a secondary analysis of physical examination data from 17,086 women aged 25–55 years at a tertiary hospital in China.
  • Compared demographic, clinical, and metabolic variables among women without thyroid or breast disease, those with a single disease, and those with thyroid-breast comorbidity.
  • Nearly half of the cohort presented with comorbidities, showing significant differences across groups for age, BMI, hypertension, diabetes, uterine fibroids, lung disease, liver disease, and kidney disease (all P < 0.05).
  • Thyroid-breast comorbidity was independently associated with uterine fibroids (OR = 2.542, 95% CI: 1.879–3.439), overweight or obesity (OR = 1.472, 95% CI: 1.211–1.788), hypertension (OR = 1.434, 95% CI: 1.063–1.934), and kidney disease (OR = 1.424, 95% CI: 1.161–1.747).

Cite This Study

Hu et al. (2026) studied this question.

synapsesocial.com/papers/6a97e275c562ede874ec6a3fhttps://doi.org/10.2147/ijwh.s613820
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