Theoretical review reveals pathways connecting infrared light to bone repair, highlighting potential optical strategies for accelerating fracture healing.
Infrared photobiomodulation (PBM) has gained increasing attention as a non-pharmacological modality capable of influencing cellular metabolism, vascular dynamics, inflammation, and tissue regeneration. While its effects on soft-tissue repair are well documented, its potential role in modulating bone biology and accelerating fracture healing remains an emerging area of investigation. This manuscript presents a comprehensive scientific framework connecting infrared light exposure to bone biology, emphasizing mitochondrial signaling, osteoblast activity, angiogenesis, extracellular-matrix formation, and biomechanical remodeling. The aim is to establish a conceptual foundation for future research in optical-based bone-regeneration strategies and to highlight the mechanistic pathways through which infrared PBM may support bone repair. Abdalkader Alkhatib BME, MBA abdalkader00@gmail.com
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Abdalkader Alkhatib (2026) studied this question.
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