Why the study?
Does high-dose radiation combined with standard multi-agent chemotherapy improve primary tumor control rates in patients with Ewing's tumor compared to less or no chemotherapy?
Population
Patients with Ewing's tumor (one group size unspecified, another group n=17)
Comparison
High doses of radiation combined with a standard… vs Less chemotherapy or no chemotherapy
Design
Cohort
Authors
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Intensive chemo with radiation may aid local control in Ewing sarcoma; leaves open need for randomized confirmation before practice change.
Does high-dose radiation combined with standard multi-agent chemotherapy improve primary tumor control rates in patients with Ewing's tumor compared to less or no chemotherapy?
Intensive chemotherapy combined with high-dose radiation correlates with improved primary tumor control in Ewing's sarcoma.
Chabora et al. (1976) studied this question.
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