Key result
Intravenous heparin significantly increased 1-week graft patency compared to saline (67% vs 19%; p<0.05) in a rabbit model of microvascular surgery.
Why the study?
Does intravenous heparin improve 7-day graft patency in a rabbit microvascular thrombosis model?
RCT (n=65)
Randomized
Does intravenous heparin improve 7-day graft patency in a rabbit microvascular thrombosis model?
Absolute Event Rate: 67% vs 19%
p-value: p=<0.05
Intravenous heparin significantly improves 1-week microarterial graft patency and reduces fibrin deposition in a rabbit thrombosis model.
No takes yet. Share an insight, caveat, or question.
Does not support clinical use; leaves open translation of heparin benefits to human microsurgery.
Greenberg et al. (1988) conducted an RCT in Vascular thrombosis in microvascular surgery (n=65). Intravenous heparin vs. Sterile saline was evaluated on 1-week graft patency (p=<0.05). Intravenous heparin significantly increased 1-week graft patency compared to saline (67% vs 19%; p<0.05) in a rabbit model of microvascular surgery.
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