Key result
Chronic inflammation, mediated by factors such as angiogenesis in the vasa vasorum, angiotensin II, and epicardial adipose tissue, plays a crucial role in the pathogenesis and progression of atherosclerosis.
This review highlights the emerging understanding that chronic inflammation, mediated by vasa vasorum and perivascular adipose tissue, is central to the pathogenesis and destabilization of atherosclerosis.
May inform anti-inflammatory trial design in atherosclerosis; leaves open clinical translation pending prospective validation.
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Masataka Sata (2011) conducted a review in Atherosclerosis. Chronic inflammation was evaluated. Chronic inflammation, mediated by factors such as angiogenesis in the vasa vasorum, angiotensin II, and epicardial adipose tissue, plays a crucial role in the pathogenesis and progression of atherosclerosis.
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