Key result
Radiofrequency catheter ablation guided by electroanatomical mapping maintained sinus rhythm in >80% of patients with mixed atrial fibrillation at an average follow-up of 11.5 months.
Why the study?
Does radiofrequency catheter ablation guided by electroanatomical mapping prevent AF recurrence in patients with mixed types of atrial fibrillation?
Observational (n=30)
Does radiofrequency catheter ablation guided by electroanatomical mapping prevent AF recurrence in patients with mixed types of atrial fibrillation?
Radiofrequency catheter ablation guided by electroanatomical mapping is a safe and effective strategy for maintaining sinus rhythm in patients with mixed types of atrial fibrillation.
May support ablation feasibility in mixed AF; hypothesis-generating and should not change practice without randomized confirmation.
Aim AF is the most common arrhythmia in clinical practice and associated with an increased long-term risk of stroke, heart failure, and all-cause mortality. Catheter ablation of AF is relatively new modality to convert AF to sinus rhythm. This study was aimed to elaborate efficacy of catheter ablation in mixed type of AF. Methods Thirty patients (age of 52 ± 8 yo) comprised of 19 paroxysmal and 11 chronic AF underwent radiofrequency catheter ablation guided by electroanatomical CARTO™ mapping system. We used step wise ablation approach with circumferential pulmonary vein isolation (PVI) as a cornerstone. Additional ablation comprised of roof line, mitral isthmus line, complex fractionated atrial electrogram (CFAE), septal line and coronary sinus ablation was done respectively if indicated. All patients were followed up to 1 year for AF recurrence. Results Circumferential PVI was successfully performed in all patients but one. Average follow up period was 11.5 months. More than 80% of all patients remain in sinus rhythm at the end of follow period which 62% of them were free from any anti-arrhythmic drug. No major complication in all patients series. Conclusion Radiofrequency ablation guided with electroanatomical mapping is effective and safe in mixed type of AF. (Med J Indones 2009;19:172-8)
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Yuniadi et al. (2010) conducted an observational in Atrial fibrillation (paroxysmal and chronic) (n=30). Radiofrequency catheter ablation guided by electroanatomical CARTO mapping system was evaluated on AF recurrence (maintenance of sinus rhythm). Radiofrequency catheter ablation guided by electroanatomical mapping maintained sinus rhythm in >80% of patients with mixed atrial fibrillation at an average follow-up of 11.5 months.
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