Key result
A novel self-positioning left atrial appendage occlusion device was feasible and safe in 5 dogs, demonstrating complete healing and occlusion at 30 days without device-related adverse events.
Why the study?
Does a novel transcatheter LAA occlusion device demonstrate feasibility and adequate healing in a canine model?
Population
5 dogs (canine model)
Design
Preclinical
Follow-up
30 days
Authors
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Supports further preclinical testing of self-positioning LAA occluders; leaves open translation to human safety and efficacy.
Does a novel transcatheter LAA occlusion device demonstrate feasibility and adequate healing in a canine model?
The novel self-positioning LAA occlusion device is feasible and safe in a canine model, demonstrating complete healing and occlusion at 30 days.
Cheng et al. (2013) studied Left atrial appendage occlusion (canine model) (n=5). Novel flexible self-apposing left atrial appendage closure device was evaluated on Feasibility of deployment and healing response. A novel self-positioning left atrial appendage occlusion device was feasible and safe in 5 dogs, demonstrating complete healing and occlusion at 30 days without device-related adverse events.
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