Key result
Arterial hypertension is associated with renal ischemia, and the reduction of renal blood supply correlates with disease severity.
Observational
Arterial hypertension is associated with renal ischemia and decreased renal blood flow, which correlates with the severity of the disease.
Should not yet change hypertension management; hypothesis-generating for renal ischemia as severity marker.
In a previous paper1we reported the results of the determination of effective renal blood flow, glomerular filtration rate and tubular excretory mass by the diodrast and inulin clearance methods in 20 patients with arterial hypertension. It was concluded that arterial hypertension is associated with renal ischemia and that the reduction of blood supply to the kidney shows a definite correlation with the severity of the disease, as indicated by the changes, in the eyegrounds, the degree of thickening of the systemic arterioles, the renal function and the elevation of systolic and diastolic blood pressures. While this previous paper was in press, the results of similar studies were published by other investigators2who also concluded that the rate of renal blood flow is decreased in most cases of hypertension. The purpose of this paper is to report the results of the determination of effective renal blood flow, glomerular
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Piero P. Foà (1943) conducted an observational in Arterial hypertension. Arterial hypertension was evaluated on Effective renal blood flow, glomerular filtration rate and tubular excretory mass. Arterial hypertension is associated with renal ischemia, and the reduction of renal blood supply correlates with disease severity.
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