Why the study?
How do renal hemodynamics and plasma renin concentration differ between patients with essential hypertension and normotensive controls?
Population
23 patients with essential hypertension and 21 control subjects
Design
Case-control
Authors
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No immediate change to hypertension evaluation; leaves open longitudinal effects of elevated renal vascular resistance.
How do renal hemodynamics and plasma renin concentration differ between patients with essential hypertension and normotensive controls?
In essential hypertension, renal vascular resistance is elevated but GFR, RPF, and plasma renin concentration are comparable to normotensive controls, with renin release appearing dependent on changes in renal vascular resistance.
Pedersen et al. (1976) studied this question.
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