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February 1, 2000Proceedings of The Society for Experimental Biology and Medicine

Regional Fat Deposition in the Legs Is Useful as a Presumptive Marker of Antiatherogenesity in Japanese

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Key result

Leg fat deposition showed a powerful negative correlation with glucose and lipid metabolites, particularly in females, suggesting its utility as a marker for obesity-associated metabolic disorders.

Why the study?

Does regional fat deposition correlate with metabolic and cardiovascular risk markers in Japanese inpatients?

Population

100 sex-matched Japanese inpatients admitted for examination of unusual results from periodic medical…

Design

Cross-sectional

Authors

MTMari TatsukawaMKMamoru KurokawaNagasaki UniversityYTYuichi Tamari

Discussion

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Overview

May inform metabolic risk assessment via leg fat in females; leaves open incremental value and causal links in prospective cohorts.

Study Design

Type

Cross-Sectional (n=100)

Structured PICO

Does regional fat deposition correlate with metabolic and cardiovascular risk markers in Japanese inpatients?

P
Population
100 sex-matched Japanese inpatients admitted for examination of obesity-related complications and unusual screening results.
E
Exposure
Evaluation of regional fat distribution (leg trunk fat ratio and arm trunk fat ratio) using dual energy X-ray absorptiometry (DEXA)
O
Outcome
Correlation between regional fat distribution and metabolites/hormones (fasting plasma glucose, HbA1c, total cholesterol, triglycerides, LDL, VLDL, atherogenic index, and apoB/A1)surrogate

Regional fat deposition in the legs, particularly in females, serves as a useful presumptive marker for metabolic and cardiovascular disorders associated with obesity.

Cite This Study

Tatsukawa et al. (2000) conducted a cross-sectional in Obesity-related metabolic and cardiovascular disorders (n=100). Regional fat deposition (leg and arm trunk fat ratios) was evaluated on Correlation between regional fat distribution and metabolic/hormonal parameters (FPG, HbA1c, TC, TG, LDL, VLDL, A.I., ApoB/A1). Leg fat deposition showed a powerful negative correlation with glucose and lipid metabolites, particularly in females, suggesting its utility as a marker for obesity-associated metabolic disorders.

synapsesocial.com/papers/6a980688161d47660415ef06https://doi.org/10.1046/j.1525-1373.2000.22321.x

Topics

Women and heart disease
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Also Consider

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