Key result
Resistance training with blood flow restriction significantly reduced stress, anxiety, and depression levels, and improved physical strength and quality of life compared to a control group in men with type 2 diabetes.
Why the study?
Psychological challenges of diabetes worsen clinical symptoms and impair quality of life, but the effects of resistance training with blood flow restriction remained to be determined.
Does 16 weeks of resistance training with blood flow restriction improve psychological symptoms, physical performance, and quality of life in men with type 2 diabetes?
RCT (n=45)
Open-label
Randomly divided into three equal groups using random allocation software and permuted block method
No
Does 16 weeks of resistance training with blood flow restriction improve psychological symptoms, physical performance, and quality of life in men with type 2 diabetes?
Absolute Event Rate: 13.01% vs 17.86%
p-value: p=<0.001
Low-intensity resistance training with blood flow restriction is as effective as traditional high-intensity resistance training in improving psychological symptoms, physical performance, and quality of life in men with type 2 diabetes.
Supports adding blood flow restriction training to type 2 diabetes care for psychological and physical gains; extends prior exercise intervention trials.
Background and Aims:The psychological challenges of diabetes exacerbate clinical symptoms and reduce quality of life.The present study aimed to determine the effect of 16 weeks of resistance training with blood flow restriction on anxiety, stress, and depression levels, physical indicators, and quality of life in males with type 2 diabetes. Materials and Methods:The present study was conducted on 45 men with type 2 diabetes who were selected through convenience sampling and randomly divided into three equal groups (15 cases each), namely traditional resistance training, resistance training with blood flow restriction, and control.Subjects in the traditional training group performed training at an intensity of 70%-80% of one repetition maximum (1RM), and the restricted group performed training at an intensity of 20%-30% of 1RM for 16 weeks.At the beginning and end of the study, the Depression, Anxiety, and Stress (DASS-21) and Quality of Life (SF-36) questionnaires were completed; moreover, upper and lower body strength were measured.Statistical analysis was performed using SPSS software (version 26) through paired t-tests, analysis of covariance, post hoc LSD, and Pearson correlation at a significance level of P≤0.05. Results:The results indicated a significant decrease in stress levels (P=0.001),anxiety (P=0.001), and depression (P=0.001); and an increase in upper body strength (P=0.002),lower body strength (P=0.01),skeletal muscle mass (P=0.002), and quality of life (P=0.001) in the two training groups, compared to the scores at pre-test.However, no significant difference was observed in the mean of these indices between the two training groups (P>0.05).Conclusion: Both traditional resistance training and resistance training with blood flow restriction effectively improve psychological symptoms and physical performance in men with type 2 diabetes.
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Nayebifar et al. (2025) conducted an RCT in Type 2 diabetes (n=45). Resistance training with blood flow restriction vs. Traditional resistance training and no-exercise control was evaluated on Stress levels (DASS-21 score) (p=<0.001). Resistance training with blood flow restriction significantly reduced stress, anxiety, and depression levels, and improved physical strength and quality of life compared to a control group in men with type 2 diabetes.
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