Key result
Microalbuminuria is associated with an increased risk of cardiovascular events and stroke, though further studies are required to establish its prognostic and therapeutic significance.
Microalbuminuria is a potential modifiable risk factor for cerebrovascular disease, highlighting the possible role of antihypertensive therapy in reducing urinary albumin excretion to mitigate risk.
Answers are grounded in this paper and cite their sources.
May aid risk stratification in cerebrovascular disease; leaves open therapeutic targeting pending prospective trials.
Stroke is potentially preventable through risk factor modification. Over the past decade, there has been considerable interest on microalbuminuria as a risk factor for chronic diseases. The concept of microalbuminuria was originally introduced, about 25 years ago, to clinical practice as a useful marker of nephropathy. Since then various studies reported an association of microalbuminuria with the increased risk of cardiovascular events and all cause of mortality in subjects with or without diabetes. The presence of microalbuminuria was related to left ventricular dysfunction, stroke, and myocardial infarction. Microalbuminuria may be a predictor of stroke but further studies are required. However data on prognostic significance and therapeutic consequence, particularly in haemorrhagic stroke are lacking. This review focuses on the importance of microalbuminuria for cerebrovascular disease, stressing the clinical and therapeutic implications using antihypertensive therapy to control the urinary albumin excretion.
No takes yet. Share an insight, caveat, or question.
Rocco et al. (2010) conducted a review in Cerebrovascular disease. Microalbuminuria was evaluated. Microalbuminuria is associated with an increased risk of cardiovascular events and stroke, though further studies are required to establish its prognostic and therapeutic significance.
Synapse has enriched 10 related papers. Consider them for comparative context: