Key result
Administration of Mannitol 1g/kg successfully restored sinus rhythm in a severe TBI patient with wide complex tachycardia after 100 J synchronized cardioversion failed.
Why the study?
Existing ventricular tachycardia treatment algorithms are based on non-traumatic patients, leaving an open question regarding the approach to treating VT in severe head trauma.
Case Report (n=1)
No
In patients with severe traumatic brain injury, wide complex tachycardia may be driven by high intracranial pressure and can respond to ICP-lowering therapy such as mannitol.
Answers are grounded in this paper and cite their sources.
May suggest mannitol for refractory wide-complex tachycardia in severe TBI; hypothesis-generating and requires prospective trials before any clinical consideration.
Background: Ventricular tachycardia (VT) is an abnormal heart rhythm that can lead to pump failure and hypoperfusion. Its causes, presentation, and treatment are well established in the literature. However, the VT treatment algorithm is based on non-traumatic patients. Due to different pathophysiology and presentation, treating VT in trauma patients should be different. Objective: The main purpose is to emphasize the approach to treating VT in severe head trauma patients. Case presentation: This case is a unique presentation of severe head trauma with a paucity of treatment approaches in the literature. In this article, we present a case of a middle-aged male patient presented to a level one trauma center with a history of falls from 2 stories height with a Glasgow Coma Scale (GCS) of 3/15. ATLS approach was followed in treating this patient, his rhythm strip showed a wide complex regular rhythm, likely representing a VT with a pulse. The patient was treated as unstable because of a decreased level of consciousness. A 100 J synchronized cardioversion was given without restoration of normal sinus rhythm, followed by Mannitol 1g/kg, treating the possibility of high intracranial pressure (ICP), after which his rhythm was restored to sinus. Conclusion: The restoration of sinus rhythm after treating the possibility of high ICP suggests that the cause of VT in this severe TBI patient was the high ICP.
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Alghamdi et al. (2023) conducted a case report in Severe Traumatic Brain Injury with Wide Complex Tachycardia (n=1). Mannitol was evaluated on Restoration of normal sinus rhythm. Administration of Mannitol 1g/kg successfully restored sinus rhythm in a severe TBI patient with wide complex tachycardia after 100 J synchronized cardioversion failed.
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