The Fading Menace of Chronic Hepatitis

EditorialsJune 1, 1975The Fading Menace of Chronic HepatitisKEITH S. HENLEY, M.D., F.A.C.P., F.R.C.P., HENRY D. APPELMAN, M.D.KEITH S. HENLEY, M.D., F.A.C.P., F.R.C.P.Search for more papers by this author, HENRY D. APPELMAN, M.D.Search for more papers by this authorAuthor, Article, and Disclosure Informationhttps://doi.org/10.7326/0003-4819-82-6-840 SectionsAboutPDF ToolsAdd to favoritesDownload CitationsTrack CitationsPermissions ShareFacebookTwitterLinkedInRedditEmail ExcerptFor this editorial we define chronic hepatitis as histologically documented, prolonged, inflammatory disease of the liver, generally sparing the intrahepatic bile ducts, and unassociated with a readily identifiable etiologic agent other than perhaps the hepatitis B antigen in tissue or serum. The words "active" or "aggressive" will be used synonymously in relation to the clinical, biochemical, or histopathologic manifestations.Our objectives are [1] to describe briefly the spectrum encompassed by this term; [2] to emphasize that clinical, biochemical, and histopathologic features do not always coincide; [3] to provide a guide for the clinician through a confusing nomenclature; and [4] to...References1. RUBINPOPPER EH: The evolution of human cirrhosis deduced from observations in experimental animals. Medicine (Baltimore) 46:163-183, 1967 CrossrefMedlineGoogle Scholar2. BOYERKLATSKIN JG: Patterns of necrosis in acute viral hepatitis. Prognostic value of bridging (subacute hepatic necrosis). N Engl J Med 283:1063-1071, 1970 CrossrefMedlineGoogle Scholar3. SOLOWAYSUMMERSKILLBAGGENSTOSS RWA: Clinical, biochemical, and histological remission of severe chronic active liver disease: a controlled study of treatments and early prognosis. Gastroenterology 63:820-833, 1972 CrossrefMedlineGoogle Scholar4. COOKMULLIGANSHERLOCK GRS: Controlled prospective trial of corticosteroid therapy in active chronic hepatitis. Q J Med 158:159-185, 1971 CrossrefGoogle Scholar5. Report from the Copenhagen Study Group for Liver Diseases. Sex, ascites and alcoholism in survival of patients with cirrhosis. N Engl J Med 291:271-273, 1974 CrossrefMedlineGoogle Scholar6. STEWARTCLUFF RL: A review of medication errors and compliance in ambulant patients. Clin Pharmacol Ther 13:463-468, 1972 CrossrefMedlineGoogle Scholar This content is PDF only. To continue reading please click on the PDF icon. Author, Article, and Disclosure InformationAffiliations: PreviousarticleNextarticle Advertisement FiguresReferencesRelatedDetails Metrics Cited ByLiver Biopsy in Hemophilia AHENRY R. LESESNE, M.D., JOHN E. MORGAN, M.D., PHILIP M. BLATT, M.D., WILLIAM P. WEBSTER, D.D.S., HAROLD R. ROBERTS, M.D.Chronic HepatitisKEITH S. HENLEY, M.D., HENRY D. APPELMAN, M.D.Corticosteroid Therapy for Chronic Active HepatitisPAUL D. BERK, M.D., F.A.C.P., E. ANTHONY JONES, M.D., M.R.C.P., PAUL H. PLOTZ, M.D., F.A.C.P., LEONARD B. SEEFF, M.D., ELIZABETH C. WRIGHT, M.P.H.Chronic Hepatitis: TherapyPATRICK J. ROONEY June 1, 1975Volume 82, Issue 6Page: 840-841 Issue Published: June 1, 1975 PDF DownloadLoading ...