Key result
Endovascular repair of small abdominal aortic aneurysms demonstrated a 1.1% 30-day mortality and 98% technical success, though 11% required reintervention at 3 years.
Why the study?
Does endovascular repair (EVAR) improve outcomes in patients with small abdominal aortic aneurysms?
Observational (n=478)
Yes
Does endovascular repair (EVAR) improve outcomes in patients with small abdominal aortic aneurysms?
EVAR for small abdominal aortic aneurysms yields good perioperative outcomes but is hampered by intermediate-term reinterventions and sac enlargement, making widespread use currently inappropriate.
Acceptable early EVAR outcomes in small AAAs should not change practice; leaves open long-term benefit versus surveillance in RCTs.
In Brief Objective: To assess the outcome of endovascular repair (EVAR) of small abdominal aortic aneurysms (AAA, ≤5.5 mm maximum diameter) in Australia. Summary Background Data: Randomized trials have suggested that small AAAs should not be treated by open surgery. EVAR is associated with less perioperative mortality than open surgery for large AAAs. We assessed the outcome of EVAR of small AAAs as part of a national audit. Methods: ASERNIP-S carried out a prospective audit of EVAR performed between November 1999 and May 2001 in Australia. A total of 478 of the 961 patients entered underwent treatment of a small AAA. Data were collected regarding preoperative characteristics, procedural outcome, and intermediate success. Median follow-up was 3.2 years. Data were analyzed using Kaplan-Meier and Cox proportional hazard analyses. Results: The 30-day mortality and technical success rates were 1.1% and 98%, respectively. Postoperative complications occurred in 29%. Survival was 84% and 52% at 3 and 5 years, respectively. Primary, assisted primary, and secondary clinical success rates were 72%, 79%, and 82%, respectively, at 3 years. Reintervention rate was 11% at 3 years; however, 15% of patients continued to have significant aortic sac enlargement. Survival was reduced in patients considered unfit for general anesthesia (odds ratio = 2.6; 95% confidence interval, 1.4–4.8, P = 0.002) or those who had elevated preoperative serum creatinine (odds ratio = 2.0; 95% confidence interval, 1.3–3.0, P = 0.001). Conclusions: EVAR can be carried with good perioperative outcome in patients with small AAA; however, intermediate success is hampered by the need for reintervention and continued aortic sac enlargement. At present, widespread treatment of small AAAs by EVAR would appear inappropriate. The management of small abdominal aortic aneurysm is controversial. We describe the outcome of a series of 478 patients treated by endovascular repair. Our findings suggest that intermediate outcome is guarded and longer follow-up is required to establish whether this form of treatment is effective for subgroups of patients with small aortic aneurysms.
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Golledge et al. (2007) conducted an observational in Small abdominal aortic aneurysms (n=478). Endovascular repair (EVAR) was evaluated on 30-day mortality. Endovascular repair of small abdominal aortic aneurysms demonstrated a 1.1% 30-day mortality and 98% technical success, though 11% required reintervention at 3 years.
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