Key result
Patient-tailored therapies, including custom-made endovascular and hybrid approaches, provided viable solutions for complex aortic arch pathologies, though high-risk cases still faced significant mortality.
Why the study?
Complex aortic pathologies present unique anatomical and clinical challenges, making the selection of endovascular, hybrid, or surgical interventions critical and difficult.
Case Report (n=5)
No
Highlights the critical role of multidisciplinary teams in tailoring endovascular, hybrid, or surgical treatments for patients with complex aortic arch anatomy.
Supports tailored endovascular and hybrid strategies for complex aortic arch disease; leaves open optimal selection and mortality reduction pending prospective data.
The treatment of complex aortic pathologies requires specialized techniques and tailored approaches due to each patient's unique anatomical and clinical challenges. The European Association for Cardiothoracic Surgery (EACTS) and the Society of Thoracic Surgeons (STS) new guidelines identify the aorta as the body's 24th organ and reiterate that multidisciplinary aortic teams are recommended for shared decision-making to determine optimal treatment strategies. Patients treated for conditions such as aneurysms, dissections, intramural hematomas, or penetrating aortic ulcers may develop complex forms over time, necessitating careful follow-up and timely corrective actions. Endovascular solutions can be favorable for older patients with complex anatomies and multiple comorbidities. However, when endovascular treatment is not feasible, hybrid treatments or open surgery must be considered if the patient's condition allows it. The risk-benefit ratio of each procedure must be carefully evaluated; choosing the best intervention or deciding not to intervene becomes a critical and challenging decision. At our Cardiac Surgery Center in Verona, a multidisciplinary team with over 20 years of experience in treating complex aortic arch pathologies extensively discussed different cases of complex aortic pathologies treated with endovascular, hybrid, or surgical approaches, emphasizing the importance of considering both anatomical and patient-specific characteristics. The decisions and treatments were often challenging, and unanimity was not always achieved, reflecting the complexity of finding the best solutions.
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Linardi et al. (2024) conducted a case report in Complex aortic arch pathologies (n=5). Patient-tailored therapy (endovascular, hybrid, or open surgery) was evaluated. Patient-tailored therapies, including custom-made endovascular and hybrid approaches, provided viable solutions for complex aortic arch pathologies, though high-risk cases still faced significant mortality.
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