Background: Success in implant therapy for replacement of one or more missing teeth has been well documented. The original surgical protocol considered a healing period of 3-6 months free from functional loading as optimal to achieve a successful osseointegration. The current scientific literature supports the concept that implants can be loaded early or immediately. Aims and Objectives: The aim of the present retrospective study was to compare early loading (within 1-2 weeks) with delayed loading (4-5 months) single-tooth implant, results after 2 years in terms of success rate by assessing peri-implant changes using clinical parameters, radiographic marginal bone level, and implant stability. Materials and Methods: A total of 20 patients (mean age = 31.15 years) treated by the implants for the rehabilitation of a single missing tooth in either jaw were examined. The test group was treated by early loading implants while the control group by delayed loading implants. Clinical and radiographic measurements were recorded around each implant. Results: At 2 years, the survival rate of implants in the control group (delayed loading implants) was 100% at 5-year follow-up while in the test group (early loading implants), it was 90%. Conclusion: It can be concluded that single-tooth implant may be loaded with predictable outcome as early as 2 weeks after installation.
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