10.5866/2019.11.10022

Oral potentially malignant disorders, in many cases, are superseded by oral carcinoma.These premalignant lesions usually manifest as erythematous or whitish patches within the oral mucosa.Histopathological grading of these lesions still remains the gold standard in diagnostic pathology; being interpreted as epithelial dysplasia.It refers to a premalignant change in epithelium characterized by a combination of cellular and architectural alterations.Histopathological grading of epithelial dysplasia poses many challenges to oral and diagnostic pathologists, including inter-and intra-observer variability and choice of optimum parameters based on which the grading should be done.Pathologists must resort to using uniform standards and defined criteria for interpretation of dysplasia.Herein, we have briefly discussed various grading systems of epithelial dysplasia.