Key result
Multipath neuromuscular electrical stimulation achieved significantly higher maximal current intensity (55 vs 46 mA, p<0.001) and lower discomfort compared to conventional stimulation in obese patients with obstructive sleep apnea.
Why the study?
Intensive care unit-acquired weakness leads to significant muscle atrophy and functional impairment, prompting evaluation of neuromuscular electrical stimulation as a therapeutic option.
Does multipath NMES improve stimulation tolerance and evoked muscle force compared to conventional NMES in severely obese patients with obstructive sleep apnea?
Population
Pre- and post-cardiac surgery patients
Comparison
Neuromuscular Electrical Stimulation vs comparator not stated
Design
Systematic review
Authors
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Multipath NMES improves tolerance and permits higher intensities versus conventional NMES in obese OSA patients; extends NMES options in this population.
RCT (n=12)
Open-label
Cross-over
No
Does multipath NMES improve stimulation tolerance and evoked muscle force compared to conventional NMES in severely obese patients with obstructive sleep apnea?
Mean Difference: 8.9
Absolute Event Rate: 55% vs 46%
p-value: p=<0.001
Multipath NMES is feasible and better tolerated than conventional NMES in severely obese patients with obstructive sleep apnea, allowing for higher stimulation intensities.
Kurian et al. (2024) conducted an RCT in Obesity and obstructive sleep apnea (n=12). Multipath neuromuscular electrical stimulation vs. Conventional neuromuscular electrical stimulation was evaluated on Maximal tolerable current intensity (mA) (MD 8.9, p=<0.001). Multipath neuromuscular electrical stimulation achieved significantly higher maximal current intensity (55 vs 46 mA, p<0.001) and lower discomfort compared to conventional stimulation in obese patients with obstructive sleep apnea.
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