Key result
Norovirus genogroup II genotype 4 (GII.4) was the most prevalent genotype (78%) circulating in Brazil, demonstrating significant viral diversity.
Cross-Sectional
Yes
Highlights the great diversity of NoV genotypes circulating in Brazil, with GII.4 being the most prevalent, emphasizing the need for virological surveillance.
Supports enhanced norovirus monitoring in Brazil; leaves open vaccine strain selection amid observed diversity.
Norovirus (NoV) infections are a major cause of acute gastroenteritis outbreaks around the world. In Brazil, the surveillance system for acute diarrhoea does not include the diagnosis of NoV, precluding the ability to assess its impact on public health. The present study assessed the circulation of NoV genotypes in different Brazilian states by partial nucleotide sequencing analysis of the genomic region coding for the major capsid viral protein. NoV genogroup II genotype 4 (GII.4) was the prevalent (78%) followed by GII.6, GII.7, GII.12, GII.16 and GII.17, demonstrating the great diversity of NoV genotypes circulating in Brazil. Thus, this paper highlights the importance of a virological surveillance system to detect and characterize emerging strains of NoV and their spreading potential.
No takes yet. Share an insight, caveat, or question.
Fioretti et al. (2011) conducted a cross-sectional in Norovirus infections. Norovirus genotypes was evaluated on Prevalence of Norovirus genotypes. Norovirus genogroup II genotype 4 (GII.4) was the most prevalent genotype (78%) circulating in Brazil, demonstrating significant viral diversity.
Synapse has enriched 5 closely related papers on similar clinical questions. Consider them for comparative context: