Key result
Maternal warfarin exposure during the first trimester resulted in fetal warfarin syndrome in an 8-year-old boy, manifesting as midface hypoplasia, delayed tooth eruption, and delayed root maturation.
Why the study?
Warfarin can cross the placenta and cause congenital abnormalities termed fetal warfarin syndrome, but insight into phenotypic variations remains needed.
Population
One 8-year-old boy with warfarin embryopathy
Design
Case report
Authors
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Alerts clinicians to dentofacial signs of fetal warfarin syndrome; extends case literature but remains hypothesis-generating.
Case Report (n=1)
This case report details the dentofacial manifestations of fetal warfarin syndrome in an 8-year-old boy, adding to the literature on phenotypic variations of warfarin embryopathy.
Rahul et al. (2022) conducted a case report in Fetal warfarin syndrome (n=1). Maternal warfarin exposure was evaluated on Dentofacial and cephalometric manifestations. Maternal warfarin exposure during the first trimester resulted in fetal warfarin syndrome in an 8-year-old boy, manifesting as midface hypoplasia, delayed tooth eruption, and delayed root maturation.
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