Key result
Nitric oxide release in the human uterine cervix changes during pregnancy and is increased in early nonviable pregnancies compared to normal uncomplicated pregnancies.
This review highlights the role of endogenous nitric oxide release in cervical ripening during pregnancy.
NO changes may inform early pregnancy assessment; leaves open whether NO modulation affects ripening or miscarriage risk.
The human uterine cervix can produce nitric oxide (NO), a free radical with an ultra-short half-life. The release of NO changes during pregnancy and is increased in early nonviable pregnancies compared to normal uncomplicated pregnancies. This review concentrates on the role of NO release in cervical ripening in pregnant women. Also some suggestions on future aspects are discussed.
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Mervi Väisänen‐Tommiska (2008) studied this question. Nitric oxide release in the human uterine cervix changes during pregnancy and is increased in early nonviable pregnancies compared to normal uncomplicated pregnancies.
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