Why the study?
Does left ventricular bypass compared to left atrial bypass reduce coronary sinus flow and oxygen consumption in dogs?
Does left ventricular bypass compared to left atrial bypass reduce coronary sinus flow and oxygen consumption in dogs?
Left ventricular bypass is more effective than left atrial bypass in reducing myocardial oxygen consumption in a canine model of left heart bypass.
LV bypass may reduce myocardial O2 consumption more than LA bypass in dogs; leaves open clinical translation.
Comparative coronary sinus flow rates and oxygen AV difference were studied in dogs undergoing left heart bypass with left atrial or left ventricular drainage at similar maximum obtainable flow rates. Left atrial bypass decreased the coronary sinus flow rates and oxygen consumption when compared with control values. These values were further decreased when left ventricular bypass was used. The oxygen consumption data were highly significant and give further evidence of increased effectiveness of complete bypass of the left ventricle in myocardial support systems.
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Don R. Miller (1974) studied this question.
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