October 1, 1962Circulation ResearchOpen Access

Partition of Coronary Flow and Cardiac Oxygen Extraction Between Coronary Sinus and Other Coronary Drainage Channels

View Full Paper

Ask AI

Bookmark

Population

Open-chest anesthetized dogs

Comparison

Physiological and pharmacological stressors… vs Baseline/control conditions

Design

Preclinical

Authors

RLRobert R. LafontantCardiovascular Institute of the South HFHarold FeinbergUniversity of Illinois Chicago LKLouis N. KatzAmerican Heart Association

Discussion

Member takes

Implication

Coronary sinus sampling accuracy is limited during stress or inotropy; leaves open its reliability for myocardial oxygen consumption assessment in humans.

Structured PICO

Population

Open-chest anesthetized dogs

Intervention

Physiological and pharmacological stressors including increased left ventricular resistance-load, augmented right ventricular effort (via balloon), induced acceleration of heart rate, and l-epinephrine exhibition

Comparator

Baseline/control conditions

Outcome

Partition of coronary flow and cardiac oxygen extraction between coronary sinus and extra-coronary-sinus channelssurrogate

Coronary sinus catheterization has limits of accuracy for assessing whole heart or left ventricular oxygen consumption, especially during stress, tachycardia, or inotropic agent use.

Cite This Study

Lafontant et al. (1962) studied this question.

synapsesocial.com/papers/6a1e86fc40bc8a3dd7690532 https://doi.org/10.1161/01.res.11.4.686

View Full Paper

Ask AI

Bookmark

Implication

Coronary sinus sampling accuracy is limited during stress or inotropy; leaves open its reliability for myocardial oxygen consumption assessment in humans.

Partition of Coronary Flow and Cardiac Oxygen Extraction Between Coronary Sinus and Other Coronary Drainage Channels

Discussion

Member takes

Implication

Structured PICO

Cite This Study

Partition of Coronary Flow and Cardiac Oxygen Extraction Between Coronary Sinus and Other Coronary Drainage Channels

Discussion

Member takes

Implication

Structured PICO

Cite This Study

Also Consider

Also Consider