Why the study?
Aortopathy is common in TOF, and the relationship between LV deformation abnormalities and aortic stiffness in corrected TOF remained to be evaluated using 3D speckle-tracking echocardiography.
Do left ventricular strains correlate with aortic elastic properties in adult patients with corrected tetralogy of Fallot compared to healthy controls?
Population
28 cTOF patients (15 pcTOF, 13 etrTOF) and 39 matched healthy adults
Comparison
pcTOF vs etrTOF vs healthy controls
Design
Comparative cross-sectional study
Key result
Corrected tetralogy of Fallot was associated with significantly lower global left ventricular longitudinal, circumferential, and area strains compared to healthy controls.
Authors
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LV strain reductions associate with aortic stiffness in corrected TOF; hypothesis-generating for early total repair benefits.
Observational (n=67)
Do left ventricular strains correlate with aortic elastic properties in adult patients with corrected tetralogy of Fallot compared to healthy controls?
Adults with corrected tetralogy of Fallot exhibit significant left ventricular deformational abnormalities that correlate with aortic stiffness, with early total reconstruction showing better LV strain parameters than early palliation-late correction.
Rácz et al. (2021) conducted an observational in Corrected tetralogy of Fallot (n=67). Corrected tetralogy of Fallot vs. Healthy adults was evaluated on Left ventricular strains and aortic elastic properties. Corrected tetralogy of Fallot was associated with significantly lower global left ventricular longitudinal, circumferential, and area strains compared to healthy controls.