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January 1, 2024European Heart Journal - Imaging Methods and PracticeOpen Access

Ascending aorta circumferential strain was significantly decreased in rTOF patients compared with controls (6.7 ± 1.9 vs. 10.1 ± 2.6, P = 0.003).

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Why the study?

In patients late after tetralogy of Fallot repair, pre-operative hypertrophy, hypoxia, ventricular interdependence, post-operative lesions, and vasculopathy may impair biventricular function.

Population

25 adult patients with repaired tetralogy of Fallot and 25 age- and gender-matched healthy controls

Comparison

Repaired tetralogy of Fallot patients vs matched healthy controls

Design

Case-control study

Authors

AVAntonio VitarelliLCLidia CapotostoFMFabio Miraldi

Discussion

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Overview

May identify aortic contributions to biventricular interactions in rTOF; leaves open whether this informs management or requires prospective validation.

Structured PICO

P
Population
25 adult patients with repaired tetralogy of Fallot (rTOF) and 25 age- and gender-matched healthy controls (total n=50).
I
Intervention
Two-dimensional (2D-STE) and three-dimensional speckle-tracking echocardiography (3D-STE)
C
Comparator
Age- and gender-matched healthy controls
O
Outcome
Left ventricular (LV) and right ventricular (RV) volumes, longitudinal strains, area strains, LV twist/rotation, and ascending aorta circumferential strain (AAo-CS)surrogate

Speckle-tracking echocardiography identifies subtle left ventricular and ascending aortic dysfunction in adults with repaired tetralogy of Fallot, which correlates with disease severity and exercise capacity.

Cite This Study

Vitarelli et al. (2024) studied this question.

synapsesocial.com/papers/6a8bc9d0d5d4290f64f48634https://doi.org/10.1093/ehjimp/qyae015
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