Key result
Between 1999 and 2011, overall HAV incidence declined from 6.0 to 0.4 cases per 100,000, while the proportion of HAV-related hospitalizations increased from 7.3% to 24.5%.
Population
US population from 1999-2011 using National Notifiable Diseases Surveillance System and Multiple Cause of…
Design
Cohort
Follow-up
1999-2011
Authors
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Rising HAV hospitalizations despite lower incidence warrant vigilance for severe disease in older adults; leaves open need for updated vaccination impact studies.
Observational
Yes
Despite a decline in overall HAV incidence, HAV-related hospitalizations and the mean age of affected individuals have increased significantly in the US.
Ly et al. (2015) conducted an observational in Hepatitis A virus infection. Hepatitis A virus infection was evaluated on Incidence of HAV infection, HAV-related hospitalization, and HAV-related mortality. Between 1999 and 2011, overall HAV incidence declined from 6.0 to 0.4 cases per 100,000, while the proportion of HAV-related hospitalizations increased from 7.3% to 24.5%.
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