Why the study?
Do human endothelial cells synthesize protein S and how is its activity modulated by various agents?
Population
Human umbilical vein endothelial cells
Comparison
Vitamin K, phorbol myristate acetate, thrombin… vs Untreated cells
Design
Preclinical
Follow-up
24 hours
Authors
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Endothelial protein S synthesis may influence local hemostasis; leaves open its in vivo modulation and clinical relevance.
Do human endothelial cells synthesize protein S and how is its activity modulated by various agents?
Human endothelial cells synthesize and secrete protein S, which can be modulated by various agents, suggesting a role in regulating hemostasis and thrombosis.
Fair et al. (1986) studied this question.
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