Key result
Primary breast angiosarcoma occurred in younger patients than secondary cases (median 43 vs 73 years, P<0.0001) and presented more often as a mass, with similar 5-year survival (46% vs 69%, P=0.8).
Why the study?
What are the clinicopathologic differences and survival outcomes between primary and secondary breast angiosarcoma?
Population
41 patients with breast angiosarcoma (27 primary, 14 secondary) treated at Mayo Clinic between 1960 and 2008.
Design
Cohort
Follow-up
5 years (survival reported at 5 years)
Authors
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Alerts clinicians to angiosarcoma in younger women with breast masses; extends distinctions but leaves optimal management open to prospective data.
Observational (n=41)
No
What are the clinicopathologic differences and survival outcomes between primary and secondary breast angiosarcoma?
Absolute Event Rate: 46% vs 69%
p-value: p=0.8
Primary breast angiosarcoma presents in younger patients and more often as a mass compared to secondary angiosarcoma, though both share a poor long-term prognosis.
Scow et al. (2010) conducted an observational in Breast angiosarcoma (n=41). Primary breast angiosarcoma vs. Secondary breast angiosarcoma was evaluated on 5-year survival (p=0.8). Primary breast angiosarcoma occurred in younger patients than secondary cases (median 43 vs 73 years, P<0.0001) and presented more often as a mass, with similar 5-year survival (46% vs 69%, P=0.8).
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