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Primary and secondary angiosarcoma of the breast are rare, aggressive malignancies with distinct clinical presentations that require aggressive surgical management, though the role of adjuvant therapies remains ill-defined.
Angiosarcoma of the breast is a rare, aggressive malignancy with distinct primary and secondary forms that require aggressive, multidisciplinary treatment due to poor overall prognosis.
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May inform surgical decisions in rare breast angiosarcomas; leaves open adjuvant strategies for prospective trials.
Angiosarcoma is a rare soft tissue tumor of the breast. It occurs in both a primary form without a known precursor, and a secondary form that has been associated to a history of irradiated breast tissue. These forms differ in many ways including median age, precipitating factors, and presentation. Both forms have a malignant behavior and a poor prognosis. The endeavor of this paper is to review what is known about the presentation, diagnostic and therapeutic modalities to date.
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Arora et al. (2014) conducted a review in Primary and secondary angiosarcoma of the breast. Surgical and adjuvant therapies was evaluated. Primary and secondary angiosarcoma of the breast are rare, aggressive malignancies with distinct clinical presentations that require aggressive surgical management, though the role of adjuvant therapies remains ill-defined.
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