Key result
Available evidence indicates that renal sympathetic denervation in patients with resistant hypertension has a favourable safety profile and is associated with substantial blood pressure reduction.
Why the study?
Does renal sympathetic denervation affect cognitive performance in patients with resistant hypertension?
Does renal sympathetic denervation affect cognitive performance in patients with resistant hypertension?
Renal sympathetic denervation is a novel catheter-based approach that appears safe and effective for blood pressure reduction in resistant hypertension.
May support RDN consideration in resistant hypertension; leaves open any cognitive effects pending randomized data.
Based on the robust preclinical and clinical data surrounding the important role of renal sympathetic nerves in various aspects of blood pressure control, a novel catheter-based approach using radiofrequency energy to target and disrupt the renal nerves selectively has been developed. Available evidence from trials in patients with resistant hypertension in whom renal denervation has been performed indicate that the procedure has a favourable safety profile and is associated with a substantial and sustained blood pressure reduction.
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Lambert et al. (2013) conducted a review in Resistant hypertension. Renal sympathetic denervation was evaluated. Available evidence indicates that renal sympathetic denervation in patients with resistant hypertension has a favourable safety profile and is associated with substantial blood pressure reduction.
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